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For having topical antibiotic activity, Chlorhexidine Gluconate is most commonly utilized as an antiseptic agent in various ointment formulations. Due to its positive charged particles, it works by reacting with negatively charged cell membrane of bacteria and destroying their cell integrity. This compound quickly gets penetrated inside bacterial cells and causes release of intracellular materials which results in cell death. Chlorhexidine Gluconate has chemical formula C34H54Cl2N10O14 with molecular weight of 897.762 g/mol. Being one of the best disinfectants, it is also used for sterilization of surgical instruments and disinfection of skin before surgery. With good water solubility, it has melting point range of 134 to 136 degrees Celsius.